🏯Khmer Traditional Medicine

Breadfruit Leaf (Slek Sakae)

Artocarpus altilis

About Breadfruit Leaf (Slek Sakae)

Breadfruit Leaf (Slek Sakae) (Artocarpus altilis) is a herb used in the Khmer Traditional Medicine tradition to help with Diabetes, Liver Support, Kidney Support, and High Blood Pressure, among 1 other condition it addresses. The leaves are the part traditionally used, taken internally.

Botanical background

Breadfruit (Artocarpus altilis) is a species of flowering tree in the mulberry and jackfruit family (Moraceae) originating in the South Pacific and eventually spreading to the rest of Oceania. British and French navigators introduced a few Polynesian seedless varieties to Caribbean islands during the late 18th century, and today it is grown in some 90 countries throughout South and Southeast Asia, the Pacific Ocean, the Caribbean, Central America and Africa. Its name is derived from the...

Source: Wikipedia, via iNaturalist

Parts used

Leaves · internal
🍵

Tea / Infusion

1–3 cups daily
  • Steep 1–2 tsp of dried Breadfruit Leaf (Slek Sakae) in freshly boiled water for 5–10 minutes.
  • Cover while steeping.
  • Strain and drink.
💧

Tincture

20–40 drops in water, 2–3× daily
  • Pack dried Breadfruit Leaf (Slek Sakae) into a jar and cover with 40–60% alcohol.
  • Seal and steep for 4–6 weeks, shaking daily.
  • Strain and store in a dark dropper bottle.
💊

Powder / Capsule

500 mg – 1 g, 1–3× daily
  • Grind dried Breadfruit Leaf (Slek Sakae) into a fine powder.
  • Fill size 00 capsules or stir into smoothies or honey.

Contraindications

  • Pregnancy & breastfeeding — insufficient safety data; consult your doctor
  • Children under 12 — therapeutic dosage not established
  • Autoimmune conditions (lupus, MS, RA) — may overstimulate immune response
  • Pre-surgery — discontinue at least 2 weeks prior (potential antiplatelet effect)
  • Active liver disease — monitor liver enzymes with long-term use
  • Significant kidney impairment — diuretic herbs may worsen renal function
  • Diabetes medications — may enhance hypoglycaemic effect; monitor blood glucose closely

Warnings

⚠️ Pregnancy & Breastfeeding

Safety during pregnancy and breastfeeding has not been established for most herbal remedies. Consult your midwife or doctor before use.

⛔ Diabetes Medications

May enhance the blood sugar–lowering effect of insulin or oral diabetes medications. Monitor blood glucose closely.

⛔ Heart & Blood Pressure Medications

May interact with antihypertensive drugs, blood thinners, or cardiac medications. Do not combine without medical guidance.

⚠️ Liver Health

Some herbs used for liver conditions can be hepatotoxic at high doses. Have liver function monitored if using long-term.

⚠️ Kidney Disease

Some diuretic herbs are contraindicated in those with kidney disease. Consult your doctor if you have impaired kidney function.

⚠️ Allergic Reactions

Discontinue immediately if you experience rash, itching, swelling, or difficulty breathing.

⚠️ Not Medical Advice

This information is for educational purposes only. Always consult a qualified healthcare provider before using herbal remedies.

Drug & herb interactions

May affect blood sugar

Watch for: Insulin and oral diabetes medications (metformin, sulfonylureas)

Additive blood-sugar-lowering effects can risk hypoglycemia — monitor glucose closely.

Processed by the liver

Watch for: Any medication that is also processed by liver enzymes (ask your pharmacist — this includes many common prescriptions)

Can alter how quickly the body clears certain medications, raising or lowering their effective dose.

May have a diuretic effect

Watch for: Diuretic medications and lithium

Additive fluid loss can affect electrolyte balance and change how the body clears lithium.

May affect blood pressure

Watch for: Antihypertensive medications (ACE inhibitors, beta-blockers, calcium channel blockers, diuretics)

Combined use can push blood pressure too high or too low — monitor readings if you take blood pressure medication.

May affect immune activity

Watch for: Immunosuppressants (for transplant or autoimmune conditions)

Immune-stimulating herbs can work against immunosuppressive therapy.

Where to find in nature

Native region

Various global regions

Climate

Varied

Habitat

Cultivated in traditional medicinal gardens, botanical gardens, and herb farms worldwide

🌿 To see Breadfruit Leaf (Slek Sakae) growing, visit botanical gardens, university plant collections, or specialist herb nurseries near you. If foraging in the wild, always work with an expert identifier — never consume a plant you are not 100% certain of.

Where to buy

In store

  • Health food stores (Whole Foods, Natural Grocers, Holland & Barrett, GNC)
  • Naturopathic clinics and integrative medicine practices
  • Specialist herbal apothecaries and herbalist practices
  • Farmers markets with herb vendors

Online

iHerb

Wide selection of standardised extracts, capsules, and powders with lab testing

Mountain Rose Herbs

Premium bulk dried herbs — certified organic, ethically sourced

Starwest Botanicals

Large selection of certified organic bulk herbs and powders

Herb Pharm

High-quality liquid extracts and tinctures, rigorous quality standards

Amazon

Convenient — verify brand certifications and check third-party testing

Etsy

Small-batch artisan herbalists, hand-harvested and wildcrafted herbs

Quality tips

When buying Breadfruit Leaf (Slek Sakae), look for: certified organic labelling, clearly stated country of origin, third-party lab testing for heavy metals and pesticides, and a batch expiry date. Standardised extracts offer consistent dosing; bulk dried herbs are more economical for regular use. Avoid very cheap, unlabelled products — quality varies enormously.